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You can read our full Privacy Policy here https: Don't have an account? You are claiming these items, please select your author name in each record. Please select author name in each record! Close Find out more. Keyword Advanced Browse all content Thesaurus. Please use quotation marks for searching phrases e. Your products All Products. Author Author Serial Subject. Previous record Next record. Actions Tools Choose a colour. This third edition, composed of 19 chapters, presents the latest scientific findings on dioxins, dibenzofurans, polychlorinated biphenyls, and related compounds, and their impact on human health.
The book comprehensively examines the many toxicological effects - including immunological, This third edition, composed of 19 chapters, presents the latest scientific findings on dioxins dioxins Subject Category: Chemicals and Chemical Groups see more details , dibenzofurans dibenzofurans Subject Category: Chemicals and Chemical Groups see more details , polychlorinated biphenyls polychlorinated biphenyls Subject Category: Chemicals and Chemical Groups see more details , and related compounds, and their impact on human health.
The book comprehensively examines the many toxicological effects - including immunological, neurological, developmental, dermatological, and cardiological - these chemicals have on health. This edition also features the latest research on other persistent organic pollutants POPs and endocrine disruptors, including brominated flame retardants polybrominated diphenyl ethers and hexabromocyclododecane , perfluorinated chemicals perfluorooctanoic acid and perfluorooctanesulfonic acid , and other endocrine disrupting chemicals similar to POPs such as bisphenol A bisphenol a Subject Category: Chemicals and Chemical Groups see more details.
Several chapters also examine specific cases of toxicity toxicity Subject Category: Commodities and Products see more details poisoning in Taiwan taiwan Subject Category: Geographic Entities see more details , and the dioxin poisoning of former Ukraine ukraine Subject Category: Geographic Entities see more details President Victor Yushchenko. Chapters in the book include the following: Miscellaneous see more details of tetrachlorodibenzodioxin and related compounds; immunomodulation by POPs; developmental neurotoxicity neurotoxicity Subject Category: Properties see more details of dioxins; epidemiological evidence on the health effects of perfluorooctanoic acid; polybrominated dibenzodioxins and dibenzofurans; epidemiological studies on cancer and exposure exposure Subject Category: Miscellaneous see more details to dioxins and related compounds; reproductive and developmental epidemiology of dioxins; bisphenol A; phthalates phthalates Subject Category: Description This text offers the most respected book available for scientific information about dioxins, dibenzofurans, and PCBs.
The new edition combines chapters on the classical dioxins and PCBs with new and emerging toxic pollutants. This edition also updates the science involved in the dioxin and PCB literature while adding new chapters on toxic pollutants such as brominated flame retardants, phthalates, and perfluorinated chemicals.
A comprehensive resource, this book provides, in one volume, essential information about these compounds written by some of the most respected and cited scientists in their fields. The Best Books of Check out the top books of the year on our page Best Books of Looking for beautiful books? Visit our Beautiful Books page and find lovely books for kids, photography lovers and more.
Dioxin-Induced Activation of Autophagy Further information on the mechanisms of dioxin toxicity can be obtained from the ultrastructural analysis of beta cells after TCDD exposure. Conclusions In the last few decades, a considerable body of epidemiological evidence has been accumulated, whose conclusions strongly suggest that exposure to dioxin and other POPs can be considered as a new risk factor for diabetes in humans in addition to the traditional lifestyle-related factors, such as excess of energy intake and a lack of exercise [ 14 , 43 ].
Open in a separate window. Conflicts of Interest The authors declare no conflict of interest. Global prevalence of diabetes: Estimates for the year and projections for The global diabetes epidemics as a consequence of lifestyle-induced low-grade inflammation. Global estimates of the prevalence of diabetes for and Environmental contaminants as etiologic factors for diabetes.
The paradox of progress: Environmental disruption of metabolism and the diabetes epidemic. Linking dioxins to diabetes: Epidemiology and biologic plausibility. Special Report on Environmental Endocrine Disruption: An Effects Assessment and Analysis. Storage and effector site for environmental pollutants. Endocrine disrupting chemicals and disease susceptibility. Endocrine disruptors in the etiology of type 2 diabetes mellitus. Persistent toxic chemicals in the US food supply.
A review of epidemiologic studies. Could low-level background exposure to persistent organic pollutants contribute to the social burden of type 2 diabetes? Evaluation of the association between persistent organic pollutants POPs and diabetes in epidemiological studies: A national toxicology program workshop review.
Persistent organic pollutants and diabetes: A review of the epidemiological evidence. Fighting a legacy of war. Serum dioxin level in relation to diabetes mellitus a mong Air Force veterans with background levels of exposure.
Serum dioxin and diabetes mellitus in veterans of Operation Ranch Hand. Serum dioxin, insulin, fasting glucose, and sex hormone-binding globulin in veterans of Operation Ranch Hand. Diabetes mellitus and 2,3,7,8-tetrachlorodibenzo- p -dioxin elimination in veterans of Operation Ranch Hand. Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia.
The Seveso studies on early and long-term effects of dioxin exposure: Health consequences of the Seveso, Italy, accident. Dioxin contamination in Seveso: The social tragedy and the scientific challenge. Mortality in a population exposed to dioxin after the Seveso, Italy, accident in Diabetes, metabolic syndrome, and obesity in relation to serum dioxin concentrations: Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice.
Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers. Impact of Agent Orange exposure among Korean Vietnam veterans. Increased rate of hospitalization for diabetes and residential proximity of hazardous waste sites. Increased risk of diabetes and polychlorinated biphenyls and dioxins: A year follow-up study of the Yucheng cohort.
Cancer, heart disease, and diabetes in workers exposed to 2,3,7,8-tetrachlorodibenzo- p -dioxin. Evaluation of diabetes mellitus, serum glucose, and thyroid function among United States workers exposed to 2,3,7,8-tetrachlorodibenzo- p -dioxin. Dioxin and diabetes mellitus: Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin. Mortality rates among workers exposed to dioxins in the manufacture of pentachlorophenol.
Re-analysis of Ranch Hand study supports reverse causation hypothesis between dioxin and diabetes. Chlorinated persistent organic pollutants, obesity, and type 2 diabetes. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: Results from the National Health and Examination Survey — Extended analyses of the association between serum concentrations of persistent organic pollutants and diabetes. Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: Associations of persistent organic pollutants with abdominal obesity in the elderly: Gamma-glutamyltransferase is a predictor of incident diabetes and hypertension: Association between serum concentrations of persistent organic pollutants and gamma glutamyltransferase: Exposure to persistent organochlorine pollutants and type 2 diabetes mellitus.
Associations of environmental exposure to dioxins with prevalent diabetes among general inhabitants in Japan. A risk factor for type 2 diabetes. Low dose of some persistent organic pollutants predicts type 2 diabetes: A nested case-control study. Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: Associations of dioxins, furans and dioxin-like PCBs with diabetes and pre-diabetes: Is the toxic equivalency approach useful?
Human biomarkers of exposure and effects—A short review. A cross-sectional study of the association between persistent organic pollutants and glucose intolerance among Greenland Inuit. Environmental toxins, a potential risk factor for diabetes among Canadian Aboriginals. A cross-sectional study of the association between persistent organochlorine pollutants and diabetes.
Molecular epidemiologic evidence for diabetogenic effects of dioxin exposure in U. Air force veterans of the Vietnam war. Chemical and toxicological evaluations of isolated and synthetic chloro derivatives of dibenzo- p -dioxin. Toxicity of chlorinated hydrocarbons and related compounds. A review including chlorinated dibenzodioxins and chlorinated dibenzofurans.
Request PDF on ResearchGate | Dioxins and health including other persistent organic pollutants and endocrine disruptors | Explores the latest science on. Request PDF on ResearchGate | Dioxins and Health: Including Other Persistent Organic Pollutants and Endocrine Disruptors, Third Edition | Scope of.
Toxicology of chlorinated dibenzo- p -dioxins. Animal studies addressing the carcinogenicity of TCDD or related compounds with an emphasis on tumour promotion. Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach. Receptor-mediated effects of chlorinated hydrocarbons.
The effects of dioxin on reproduction and development. The aryl hydrocarbon receptor pathway and sexual differentiation of neuroendocrine functions. Toxicity of 2,3,7,8 tetrachlorodibenzo- p -dioxin in rhesus monkeys Macaca mulatta following a single oral dose.
Toxicity of 2,3,7,8-tetrachlorodibenzo- p -dioxin in the golden Syrian hamster. Aggravation after ventromedial hypothalamic lesion. Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance. Characterization of the wasting syndrome in rats treated with 2,3,7,8-tetrachlorodibenzo- p -dioxin.
Characterization of the hyperlipidemia in guinea pigs induced by 2,3,7,8-tetrachlorodibenzo- p -dioxin. TCDD 2,3,7,8-tetrachlorodibenzo- p -dioxin reduces lipoprotein lipase activity in the adipose tissue of the guinea pig. Involvement of SREBPs in 2,3,7,8-tetrachlorodibenzo- p -dioxin-induced disruption of lipid metabolism in male guinea pig.
Identification of aryl hydrocarbon receptor binding targets in mouse hepatic tissue treated with 2,3,7,8-tetrachlorodibenzo- p -dioxin. Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver. Effects of 2,3,7,8-tetrachlorodibenzo- p -dioxin on serum insulin and glucose levels in the rabbit.
The use of c-src knockout mice for the identification of the main toxic signaling pathway of TCDD to induce wasting syndrome. The stimulation of tumor necrosis factor and inhibition of glucose transport and lipoprotein lipase in adipose cells by 2,3,7,8-tetrachlorodibenzo- p -dioxin. Studies on the cell treatment conditions to elicit lipolytic responses from 3T3-L1 adipocytes to TCDD, 2,3,7,8-tetrachlorodibenzo- p -dioxin. Expression of hypothalamic neuropeptides after acute TCDD treatment and distribution of Ah receptor repressor.
Assessment by c-Fos immunostaining of changes in brain neural activity induced by 2,3,7,8-tetrachlorodibenzo- p -dioxin TCDD and leptin in rats. A single administration of 2,3,7,8-tetrachlorodibenzo- p -dioxin that produces reduced food and water intake induces long-lasting expression of corticotropin-releasing factor, arginine vasopressin, and proopiomelanocortin in rat brain.
TCDD 2,3,7,8-tetrachlorodibenzo- p -dioxin causes reduction in glucose uptake through glucose transporters on the plasma membrane of the guinea pig adipocyte. Effects of 2,3,7,8-tetrachlorodibenzo- p -dioxin on adipogenic differentiation and insulin-induced glucose uptake in 3T3-L1 cells. Evidence for the involvement of arylhydrocarbon receptor-mediated alteration of glucose transportation.
Dioxin affects glucose transport via the arylhydrocarbon receptor signal cascade in pluripotent embryonic carcinoma cells. Mechanism of action of dioxin-type chemicals, pesticides, and other xenobiotics affecting nutritional indexes. Dose-response and time course of hypothyroxinemia and hypoinsulinemia and characterization of insulin hypersensitivity in 2,3,7,8-tetrachlorodibenzo- p -dioxin TCDD -treated rats. Some endocrine and morphological aspects of the acute toxicity of 2,3,7,8-tetrachlorodibenzo- p -dioxin TCDD Toxicol.