Is It Game Over For MRSA?
Stars Screen Binge Culture Media. Tech Innovate Gadget Mission: Chat with us in Facebook Messenger. Find out what's happening in the world as it unfolds. This scanning electron micrograph SEM depicted numerous clumps of methicillin-resistant Staphylococcus aureus bacteria, commonly referred to by the acronym, MRSA; Magnified x.
Methicillin-resistant Staphylococcus aureus MRSA bacteria are resistant to all beta-lactam antibiotics such as methicillin, penicillin, oxacillin, and amoxicillin. Staphylococcus aureus bacteria are commonly found on the skin and in the noses of healthy people. Skin infections from staph bacteria are called staph infections; staph bacteria are one of the most common causes of skin infection in the United States.
Staph bacteria are a common cause of pneumonia, surgical wound and bloodstream infections. Most of these infections can be treated without antibiotics. Twenty-five to thirty percent of the population is colonized with staph, and less than two percent is colonized with MRSA.
Colonized means bacteria is present but doesn't cause infection. Published online Jan Author information Article notes Copyright and License information Disclaimer.
Received Jun 17; Accepted Jan 4. This article has been cited by other articles in PMC. Osteomyelitis, Septic, Staphylococcus, Methicillin, Resistance. Introduction Recent increase in the incidence of osteomyelitis and septic arthritis due to a rise in predisposing factors like diabetes mellitus and peripheral vascular disease, is a matter of great concern.
All the patients of acute haematogenous osteomyelitis or septic arthritis treated during the study period were enrolled for the study. A total of patients were enrolled, out of which 49 were excluded as 10 patients were already on antibiotics and 39 patients did not have complete case records.
Cases with implant related infections, perioperative and postoperative infections were also excluded from study. After exclusion, we enrolled 81 patients in this study 57 prospective and 24 retrospective. Five ml of venous blood was collected at the time of presentation and was sent for culture and sensitivity studies and analysis of haematological parameters.
How to Avoid a Staph Infection and MRSA
ESR was estimated by Wintrobe method. C-reactive protein was estimated by nephelometer. The study parameters were categorised into parametric and non parametric by doing test of normality — Kolmogorov Smirnov test. Parameters found normally distributed were further analysed by univariate analysis using Student T-test.
1. Introduction
Parameters which showed non normal distribution were further analysed by univariate analysis using Mann Whitney U test. Receiver operating characteristic curve analysis was performed for each independent significant predictor to determine the area under the curve. Statistical analysis was performed using SPSS software version Table 1 Frequencies of various causative agents of acute bone and joint infections found in our study.
Open in a separate window. Table 2 Comparison of central tendencies of parameters among MRSA and others and p value after univariate analysis of parameters. P value is significant for the parameters in bold.
Discussion Staphylococcus aureus has been the most common cause of acute haematogenous osteoarticular infections. This can be a useful guide to early institution of appropriate antibiotic. Conflicts of interest All authors have none to declare. Changing patterns of acute hematogenous osteomyelitis and septic arthritis: Etiology of septic arthritis in children: Am J Emerg Med.
Community-associated, methicillin-susceptible, and methicillin-resistant Staphylococcus aureus bone and joint infections in children: J Pediatr Orthop Part B. Am J Infect Control. Indian J Med Res. Spread of methicillin-resistant Staphylococcus aureus between the community and the hospitals in Asian countries: Community-associated methicillin-resistant Staphylococcus aureus in acute musculoskeletal infection in children: Deep venous thrombosis associated with acute hematogenous osteomyelitis in children. Orthop Traumatol Surg Res.
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Epidemiology of acute hematogenous osteomyelitis in children: Changing epidemiology of neonatal septic arthritis. J Orthop Surg [Internet] [cited Jul 21];12 1. Changing trends in acute osteomyelitis in children: Haematogenous acute and subacute paediatric osteomyelitis a systematic review of the literature. J Bone Jt Surg Br. Venous thrombosis associated with Staphylococcal osteomyelitis in children. Comparative severity of pediatric osteomyelitis attributable to methicillin-resistant versus methicillin-sensitive Staphylococcus aureus.
Osteoarticular infections with staphylococcus aureus secreting Panton-Valentine leucocidin.