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Preview this item Preview this item. English View all editions and formats Summary: Non-alcoholic fatty liver disease is a common cause of chronic liver disease, and its incidence is rising worldwide.
Understanding its pathogenesis, biochemical parameters, histological grading and staging, and its management is a vital issue in today's clinical practice. It appears to be linked directly to the growing epidemic of obesity in adults as well as in children. However, some researchers consider that.
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Add a review and share your thoughts with other readers. Linked Data More info about Linked Data. Home About Help Search. Privacy Policy Terms and Conditions. Management of Benign Biliary Stenosis and Injury. Cellular Injury in Liver Diseases. Schiff's Diseases of the Liver. Gallstone Disease and its Management. Pathology of the Bile Duct.
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Item s unavailable for purchase. Please review your cart. A detailed literature search of published medical reports in English language was performed on electronic databases such as PubMed and Cochrane, from to using relevant search terms. The search yielded 25 relevant articles whose full texts were retrieved and evaluated.
Lifestyle intervention is generally considered the first line therapy for patients with NAFLD without steatohepatitis while pharmacotherapy in addition to lifestyle intervention is suggested for patients with non-alcoholic steatohepatitis NASH. Current therapies are directed towards improving the metabolic parameters which contribute to disease pathogenesis. Pharmacological therapies for NAFLD and NASH include antioxidants such as vitamin E and ursodeoxycholic acid; insulin sensitizers such as metformin and thiazolidinones, weight loss drugs like orlistat and consideration of bariatric surgery for morbidly obese patients.
Further, prospective studies will fill the various missing links associated with management of NAFLD in Indian patients in a more effective manner. Nonalcoholic fatty liver disease in India — a lot done, yet more required!.
Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. Mayo clinic experience with a hitherto unnamed disease. AGA technical review on nonalcoholic fatty liver disease.
Neuschwander-Tetri B, Caldwell S. Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease. Prevalence of and risk factors for hepatic steatosis in Northern Italy.
Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians. The clinicopathological profile of Indian patients with nonalcoholic fatty liver disease NAFLD is different from that in the west. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.
Proc Nat Acad Sci. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med. Tilg H, Diehl A.
Cytokines in alcoholic and nonalcoholic steatohepatitis. N Eng J Med. Assessment of insulin resistance and effect of metformin in nonalcoholic steatohepatitis: Pathogenesis of non-alcoholic fatty liver disease. Singh S, Panigrahi M. Accessed on 14th January Byrne C, Targher G. Non-alcoholic fatty liver disease and metabolic syndrome-position paper of the Indian national association for the study of the liver, endocrine society of India, Indian college of cardiology and Indian society of gastroenterology.
J Clin Exp Hepatol. Management of chronic liver disease by general practitioners in southern Italy: Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Improving nonalcoholic gatty liver disease management by general practioners: J Gastrointest Liver Dis. Clinical features and natural history of nonalcoholic steatosis syndromes.
Mishra P, Younossi Z. Interobserver and intraobserver variability in the sonographic assessment of fatty liver.
Protocol for measurement of liver fat by computed tomography. Magnetic resonance spectroscopy to measure hepatic triglyceride content: Am J Physiol Endocrinol Metab. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: